Ursodeoxycholic acid in liver diseases
نویسندگان
چکیده
منابع مشابه
Ursodeoxycholic acid in the treatment of liver diseases.
Ursodeoxycholic acid is a dihydroxy bile acid with a rapidly expanding spectrum of usage in acute and chronic liver diseases. The various mechanisms of action of this hydrophilic bile acid include direct cytoprotection, detergent action on dysfunctional microtubules, immunomodulation and induction of hypercholeresis. Its efficacy in primary biliary cirrhosis and primary sclerosing cholangitis a...
متن کاملNew therapies Ursodeoxycholic acid in the treatment of liver diseases
Ursodeoxycholic acid is a dihydroxy bile acid with a rapidly expanding spectrum of usage in acute and chronic liver diseases. The various mechanisms of action of this hydrophilic bile acid include direct cytoprotection, detergent action on dysfunctional microtubules, immunomodulation and induction ofhypercholeresis. Its efficacy in primary biliary cirrhosis and primary sclerosing cholangitis as...
متن کاملUrsodeoxycholic acid in chronic liver disease.
The hydrophilic bile acid ursodeoxycholic acid has recently been shown to reduce biochemical markers of both cholestasis and hepatocellular damage in patients with chronic liver diseases. The most compelling evidence available is for chronic cholestatic liver diseases, in particular primary biliary cirrhosis, primary sclerosing cholangitis, and cholestasis associated with cystic fibrosis. The e...
متن کاملUrsodeoxycholic Acid in Treatment of Non-cholestatic Liver Diseases: A Systematic Review
Aims: To systematically evaluate the literature for evidence to support the use of bile acids in non-cholestatic liver conditions. Methods: Searches were conducted on the databases of Medline (1948-March 31, 2015), Embase (1980-March 31, 2015) and the Cochrane Central Register of Controlled Trials, and on Google and Google Scholar to identify articles describing ursodeoxycholic acid (UDCA) and ...
متن کاملUrsodeoxycholic Acid (UDCA) in Biliary Diseases: A Clinical Review
Ursodeoxycholic acid (UDCA) is an established and accepted treatment of biliary diseases such as gallstones and primary biliary cirrhosis. Mechanisms of action of UDCA are not so far completely elucidated. UDCA tablets are indicated for the dissolution of small to medium sized radiolucent, cholesterol-rich gall-stones in patients with a functioning gall bladderand in the treatment of primary bi...
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ژورنال
عنوان ژورنال: Gastroenterology Review
سال: 2012
ISSN: 1895-5770
DOI: 10.5114/pg.2012.29879